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Development of a Hepatitis B Virus Reporter System to Monitor the Early Stages of the Replication Cycle
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Letter to the editor: Alu-PCR design may have compromised detection of integrated core HBV DNA
Gustaf E Rydell1, Johan Ringlander1, Simon B Larsson1
1Department of Infectious Diseases, Institute of Biomedicine, University of Gothenburg Sahlgrenska Academy, Gothenburg, Sweden.
Hepatology (Baltimore, Md.)
|March 23, 2022
Abstract
No abstract available in PubMed .
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Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...

