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Quetiapine-related acute lung injury: A case report
Yi-Xia Huang1, Guo-Xin He2, Wen-Jing Zhang2
1Intensive Care Unit, The Third Affiliated Hospital, Wenzhou Medical University, Ruian 330381, Zhejiang Province, China. 378206482@qq.com.
Background:
Quetiapine, known as a non-classical antipsychotic drug, is frequently used for the treatment of mental diseases, such as schizophrenia, bipolar disorder, and major depressive disorder. Acute lung injury, a rarely reported side effect of quetiapine, is described in this case report.
Case Summary:
Due to terminal delirium, a 66-year-old man took a large dose of quetiapine and then developed severe pulmonary disease. His symptoms were not resolved after routine treatment, such as antibiotics, diuretic, and supportive therapies. Quetiapine-related acute lung injury was therefore suspected and hormonal therapy was initiated. Subsequently, his symptoms were alleviated and the radiological results improved dramatically.
Conclusion:
Our findings in the present report highlight a potential adverse effect of quetiapine, drug-related acute lung injury, which deserves awareness in clinical practice.
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