Natural genetic engineering: A programmed chromosome/DNA elimination

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Updated: Sep 29, 2025

Generation of Genomic Deletions in Mammalian Cell Lines via CRISPR/Cas9
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Generation of Genomic Deletions in Mammalian Cell Lines via CRISPR/Cas9

Published on: January 3, 2015

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Malgorzata Kloc1, Jacek Z Kubiak2, Rafik M Ghobrial3

  • 1The Houston Methodist Research Institute, Houston, TX, USA; The Houston Methodist Hospital, Department of Surgery, Houston, TX, USA; The University of Texas, MD Anderson Cancer Center, Department of Genetics Houston, TX, USA.

Developmental Biology
|March 24, 2022
PubMed

Keywords:
B chromosomesChromosome driveChromosome eliminationDiminutionGene silencingProgrammed DNA eliminationRepetitive sequencesSuper-mendelian inheritance

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