Venoarterial extracorporeal membrane oxygenation for septic cardiomyopathy caused by Pasteurella multocida infection:

Ai Nagai1, Takeshi Adachi2, Yoshiyuki Nishizawa1

  • 1Department of Anesthesiology, Kitasato University, School of Medicine, 1-15-1 Kitasato Minami-ku, Sagamihara City, Kanagawa, 252-0375, Japan.

Journal of Anesthesia
|March 24, 2022
PubMed

Insights

Kissing a pet dog led to a severe Pasteurella multocida infection, causing sepsis and cardiogenic shock. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) successfully supported the patient until recovery, highlighting its potential in critical cases.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Critical Care Medicine

Background:

  • Pasteurella multocida, a gram-negative coccobacillus, is typically transmitted via animal bites.
  • Infections can lead to severe systemic complications, including sepsis and cardiovascular compromise.

Observation:

  • A 62-year-old man developed Pasteurella multocida sepsis and refractory cardiogenic shock after kissing his pet dog.
  • Initial treatment for cervical cellulitis and septic shock was insufficient.

Findings:

  • The patient required venoarterial extracorporeal membrane oxygenation (VA-ECMO) for cardiovascular support.
  • Hemodynamic status improved significantly after VA-ECMO initiation, with successful weaning after 6 days.

Implications:

  • Pasteurella multocida infections can cause severe sepsis-induced myocardial dysfunction even in healthy adults.
  • VA-ECMO is a viable therapeutic option for managing refractory cardiogenic shock in sepsis.
  • Early recognition and aggressive management are crucial for favorable outcomes in severe Pasteurella infections.

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