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Updated: Sep 29, 2025

Echocardiographic Assessment of Cardiac Anatomy and Function in Adult Rats
Published on: December 13, 2019
Echocardiographic Assessment of Atrial Function: From Basic Mechanics to Specific Cardiac Diseases
Katsuji Inoue1, Hiroshi Kawakami1, Yusuke Akazawa1
1Department of Cardiology, Pulmonology, Hypertension & Nephrology, Ehime University Graduate School of Medicine, Toon 791-0295, Ehime, Japan.
Insights
The left atrium (LA) is crucial for cardiac performance, acting as a pump, reservoir, and conduit. Assessing LA function via echocardiography aids in understanding heart failure and other cardiac conditions.
Area of Science:
- Cardiology
- Cardiac Physiology
- Echocardiography
Background:
- The atria function as critical buffer chambers for ventricular filling.
- Left atrial (LA) function significantly impacts overall cardiac performance and is linked to heart failure.
- Understanding atrial mechanics is essential for diagnosing and managing cardiac diseases.
Purpose of the Study:
- To review the contribution of the left atrium to cardiac performance.
- To evaluate the assessment of LA function using echocardiography.
- To discuss LA dysfunction in complex cardiac conditions like cardiac amyloidosis and adult congenital heart disease.
Main Methods:
- Echocardiography for assessing left atrial (LA) function.
- Speckle tracking echocardiography for LA strain measurement.
- Analysis of LA pressure-volume relationships.
Main Results:
- LA strain measurement evaluates the booster pump, reservoir, and conduit functions of the atrium.
- LA reservoir strain demonstrates prognostic value in various cardiac diseases.
- Echocardiographic evaluation provides insights into LA mechanics and function.
Conclusions:
- Left atrial function is vital for maintaining cardiac performance.
- Echocardiography, particularly LA strain analysis, is a valuable tool for assessing LA function.
- Understanding LA dysfunction is critical in managing challenging cardiac diseases.
Abstract:
The left and right atria serve as buffer chambers to control the flow of venous blood for ventricular filling. If an atrium is absent, blood does not flow effectively into the ventricle, leading to venous blood retention and low cardiac output. The importance of atrial function has become increasingly recognized, because left atrial (LA) function contributes to cardiac performance, and loss of LA function is associated with heart failure. LA volume change has been used for LA function assessment in experimental and clinical studies. In conjunction with LA pressure, the LA pressure-volume relationship provides a better understanding of LA mechanics. LA strain measurement by speckle tracking echocardiography was introduced to evaluate three components of LA function as a (booster) pump, reservoir and conduit. Furthermore, increasing evidence supports the theory that LA reservoir strain has prognostic utility in various cardiac diseases. In this review, we summarize LA contribution to maintain cardiac performance by evaluating LA function with echocardiography according to our experiences and previous reports. Furthermore, we discuss LA dysfunction in challenging cardiac diseases of cardiac amyloidosis and adult congenital heart disease.
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