Related Experiment Video
Updated: Sep 29, 2025

Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound 30/45MHZ System
Published on: May 5, 2018
Screening for Cardiovascular Disease in Pregnancy: Is There a Need?
Melissa E Chambers1, Madushka Y De Zoysa2, Afshan B Hameed2
1Department of Obstetrics and Gynecology, University of California Irvine, Orange, CA 92868, USA.
Insights
Maternal deaths from cardiovascular disease (CVD) are rising. Universal screening during pregnancy and postpartum can identify at-risk women, improving outcomes and reducing costs.
Area of Science:
- Obstetrics and Gynecology
- Cardiology
- Public Health
Background:
- Maternal mortality in the U.S. is increasing, with cardiovascular disease (CVD) as a leading cause of pregnancy-related deaths.
- Delayed diagnosis of CVD in pregnant women is common due to overlapping symptoms with normal pregnancy.
- Existing risk models often require a prior CVD diagnosis, missing many women who develop CVD during pregnancy or postpartum.
Purpose of the Study:
- To propose universal cardiovascular disease (CVD) screening for all pregnant and postpartum women.
- To identify women at high risk for CVD during the antepartum and postpartum periods.
- To enhance patient and healthcare provider education and awareness regarding CVD in pregnancy.
Main Methods:
- Utilizing a validated algorithm developed by the California Maternal Quality Care Collaborative (CMQCC) for CVD risk stratification.
- Implementing universal screening in both antepartum and postpartum care settings.
- Stratifying patients into low or high-risk categories based on screening results.
Main Results:
- The CMQCC algorithm has demonstrated validation across diverse patient populations.
- Universal screening aims to proactively identify undiagnosed CVD risk.
- Early identification facilitates targeted interventions and management strategies.
Conclusions:
- Universal CVD screening is a critical tool to combat rising maternal mortality and morbidity.
- This approach can significantly reduce healthcare costs associated with severe maternal complications.
- Increased awareness and education are essential for effective CVD management in pregnancy and postpartum.
Abstract:
Maternal mortality in the United States has been on the rise. Every year, about 700 women die from pregnancy-related complications. Cardiovascular disease (CVD) accounts for a large majority of pregnancy-related deaths driven by the lack of recognition and delays in diagnosis due to the overlap of normal pregnancy symptoms with those of CVD. Risk factors for CVD including race, advanced maternal age, hypertension, diabetes, obesity, socioeconomic status, and geographic region play an important role in CVD-related deaths. Several risk assessment models are available to stratify women with a known diagnosis of CVD. However, most women who die from CVD during pregnancy or the postpartum period do not have a prior diagnosis of CVD, and cardiomyopathy is an important contributor. The California Maternal Quality Care Collaborative (CMQCC) developed an algorithm to screen all pregnant and postpartum women to allow stratification into low or high risk for CVD. The algorithm has been validated in diverse patient populations. We propose universal CVD screening for all women in the antepartum and postpartum period to identify women at risk and to provide education and awareness for both patients and healthcare providers. This screening tool would work to reduce the increasing rates of severe maternal mortality and morbidity while having a significant impact on healthcare costs in the United States.
Related Concept Videos
Assessment of the Cardiovascular System I: Subjective Data
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Assessment of the Cardiovascular System II: Inspection
Head and Neck
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
Exercise Stress Test
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes

