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Updated: Sep 29, 2025
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Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
Published on: June 28, 2024
520
Taurine: A Maternally Derived Nutrient Linking Mother and Offspring
Shiro Tochitani1,2,3,4
1Division of Health Science, Graduate School of Health Science, Suzuka University of Medical Science, Suzuka 513-8670, Japan.
Metabolites
|March 24, 2022
Summary
Maternally supplied taurine is crucial for mammalian offspring development, influencing adult traits and long-term health. Environmental factors can disrupt this vital nutrient transfer, impacting offspring well-being.
Area of Science:
- Developmental biology
- Nutritional science
- Maternal-fetal medicine
Background:
- Mammals synthesize taurine but fetuses/infants have limited capacity.
- Offspring rely on maternal taurine via placenta and breast milk.
- Maternal taurine is essential for development and shapes adult traits.
Purpose of the Study:
- Review taurine's developmental functions.
- Discuss maternal-offspring taurine transport mechanisms.
- Examine environmental impacts on taurine transfer and offspring health.
Main Methods:
- Literature review of taurine's role in development.
- Analysis of maternal-fetal and maternal-infant taurine transfer.
- Discussion of environmental factors and their influence.
Main Results:
- Maternally derived taurine is critical for fetal and infant development.
- Environmental factors like maternal obesity can impair taurine transfer.
- Perinatal taurine availability influences offspring health and disease risk.
Conclusions:
- Maternal taurine is essential for healthy offspring development.
- Disrupted taurine transfer can have lifelong consequences.
- Taurine's role in gut microbiota and DOHaD warrants further investigation.
Keywords:
2-aminoethanesulfonic acidGABAA receptorsdevelopmental programmingglycine receptorsneural progenitorneural stem cellobesityperinatal nutritionplacental transfertaurine transporterMore Related Videos
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