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Cell Culture Process Scale-Up Challenges for Commercial-Scale Manufacturing of Allogeneic Pluripotent Stem Cell

Brian Lee1, Sunghoon Jung1, Yas Hashimura1

  • 1PBS Biotech, Inc., Camarillo, CA 93012, USA.

Bioengineering (Basel, Switzerland)
|March 24, 2022
PubMed

Keywords:
allogeneic cell therapycell aggregatecomputational fluid dynamicsdifferentiationexpansionhomogeneous hydrodynamic environmenthuman embryonic stem cellinduced pluripotent stem cellmedium exchangeoxygenationscalable manufacturingscale upshear stresssingle-use bioreactorturbulent energy dissipation ratevertical-wheel

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