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Related Experiment Video

Updated: Sep 29, 2025

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
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Smartphone-Based Biosensor Devices for Healthcare: Technologies, Trends, and Adoption by End-Users.

Rossana E Madrid1, Fernando Ashur Ramallo1, Daniela E Barraza1

  • 1Laboratorio de Medios e Interfases (LAMEIN), DBI, FACET, Universidad Nacional de Tucumán, Instituto Superior de Investigaciones Biológicas (INSIBIO), CONICET, Av. Independencia 1800, San Miguel de Tucuman 4000, Argentina.

Bioengineering (Basel, Switzerland)
|March 24, 2022
PubMed
Summary

Smart biosensor technology for healthcare is advancing rapidly, but patent filings have declined. This review explores current developments and barriers to market adoption for these crucial health monitoring tools.

Keywords:
POC devicescommercial biosensorselectrochemical biosensorsoptical biosensorspaper-based biosensorsregulations

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Area of Science:

  • Biomedical Engineering
  • Sensor Technology
  • Digital Health

Background:

  • Smartphone-based biosensors represent a significant advancement in modern healthcare, offering sensitive and effective diagnostic capabilities.
  • Despite technological progress, a notable decline in patent filings for smart biosensors in healthcare has been observed in recent years.

Purpose of the Study:

  • To review the current state-of-the-art of various smartphone-based biosensor technologies across different development stages.
  • To critically analyze the reasons behind the limited market entry of many smart biosensor technologies.

Main Methods:

  • Comprehensive literature review of recent smartphone-based biosensor developments.
  • Analysis of patent and patent application trends in smart biosensors for healthcare.
  • Critical evaluation of technical and end-user adoption challenges hindering commercialization.

Main Results:

  • While numerous effective smartphone biosensor technologies exist, commercial availability remains limited.
  • A decrease in patent applications suggests potential stagnation or challenges in the translation of research to market.

Conclusions:

  • Significant evolution in smart biosensor technology has not translated into widespread market presence.
  • There is a critical need to enhance technology transfer, application, and end-user adoption to realize the full potential of smartphone biosensors in healthcare.