Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

715
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
715
Equilibrium and Balance01:15

Equilibrium and Balance

5.1K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
5.1K
The Vestibular System01:29

The Vestibular System

40.3K
The vestibular system is a set of inner ear structures that provide a sense of balance and spatial orientation. This system is comprised of structures within the labyrinth of the inner ear, including the cochlea and two otolith organs—the utricle and saccule. The labyrinth also contains three semicircular canals—superior, posterior, and horizontal—that are oriented on different planes.
40.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longevity and Volume Expansion of Hyaluronic Acid Dermal Fillers: A Cross-sectional 3-dimensional Magnetic Resonance Imaging Study.

Plastic and reconstructive surgery. Global open·2026
Same author

CGRP-Targeted Therapy in Vestibular Migraine-How Strong Is the Evidence?

European journal of neurology·2026
Same author

Cup-to-Disc Ratio Is Associated with Disability in Multiple Sclerosis: A Combined OCT and Subjective Visual Vertical Study.

Medicina (Kaunas, Lithuania)·2026
Same author

Persistent postural-perceptual dizziness: subjective-objective dissociation and response to neurologist-led multimodal therapy.

Journal of neurology·2026
Same author

Radiological Features of Human Papillomavirus (HPV)-Positive and HPV-Negative Oropharyngeal Squamous Cell Carcinoma (OPSCC)-Considerations for Multimodal Analysis.

Cancers·2026
Same author

Clinical Presentation and Tumour Burden in Head and Neck Sarcomas: Implications for Early Diagnosis and Referral.

Cancers·2026

Related Experiment Video

Updated: Sep 29, 2025

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
07:40

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

Published on: January 12, 2022

5.2K

Autoimmune Vestibulopathy-A Case Series.

Surangi Mendis1,2, Nicola Longley3,4, Simon Morley5

  • 1Department of Neuro-Otology, Royal National ENT and Eastman Dental Hospitals, UCLH, London WC1E 6DG, UK.

Brain Sciences
|March 25, 2022
PubMed
Summary

Autoimmune inner ear disease (AIED) can cause vestibular problems. This study reports three cases, including one linked to the Pfizer-BioNTech COVID-19 vaccine, highlighting varied presentations of this rare condition.

Keywords:
AIEDCOVID-19Cogan syndromeautoimmuneulcerative colitisvaccinationvestibularvestibulopathy

More Related Videos

A Unified Methodological Framework for Vestibular Schwannoma Research
08:43

A Unified Methodological Framework for Vestibular Schwannoma Research

Published on: June 20, 2017

7.5K
Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform
10:12

Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform

Published on: May 23, 2013

16.0K

Related Experiment Videos

Last Updated: Sep 29, 2025

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
07:40

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

Published on: January 12, 2022

5.2K
A Unified Methodological Framework for Vestibular Schwannoma Research
08:43

A Unified Methodological Framework for Vestibular Schwannoma Research

Published on: June 20, 2017

7.5K
Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform
10:12

Three Dimensional Vestibular Ocular Reflex Testing Using a Six Degrees of Freedom Motion Platform

Published on: May 23, 2013

16.0K

Area of Science:

  • Otolaryngology
  • Immunology
  • Neurology

Background:

  • Autoimmune inner ear disease (AIED) is rare, with poorly understood causes and treatments.
  • Current diagnostic criteria for AIED primarily focus on auditory symptoms and response to immunosuppression.
  • Vestibular symptoms in AIED are often overlooked despite their potential impact.

Observation:

  • This study details three cases of vestibulopathy in patients with autoimmune inner ear conditions.
  • One case describes autoimmune inner ear pathology temporally associated with Pfizer-BioNTech SARS-CoV-2 vaccination.
  • The presentations of vestibular impairment in these cases were notably variable.

Findings:

  • Vestibular dysfunction can be a significant manifestation of autoimmune inner ear disease.
  • Autoimmune inner ear conditions may arise following SARS-CoV-2 vaccination.
  • The clinical spectrum of vestibular involvement in AIED is broader than currently recognized.

Implications:

  • Further research is needed to understand the pathogenesis and diagnostic criteria for AIED, particularly regarding vestibular involvement.
  • Clinicians should consider AIED in patients presenting with unexplained vestibular symptoms, especially those with a history of autoimmune disease or recent vaccination.
  • Early recognition and management of vestibular symptoms in AIED may improve patient outcomes.