Healthcare Workers' Knowledge and Perception of the SARS-CoV-2 Omicron Variant: A Multinational Cross-Sectional Study

Area of Science:

• Infectious Diseases
• Public Health
• Epidemiology

Background:

• The emergence of the SARS-CoV-2 Omicron variant (B.1.1.529) in late 2021 led to rapid global dominance.
• Existing COVID-19 vaccines demonstrated reduced efficacy against the Omicron variant, highlighting the need for updated strategies.
• Understanding healthcare workers' (HCWs) knowledge and perceptions is vital for effective public health responses to new variants.

Purpose of the Study:

• To assess the awareness, knowledge, and perceptions of healthcare workers regarding the SARS-CoV-2 Omicron variant.
• To identify factors influencing HCWs' understanding and views on the Omicron variant.
• To inform the development of targeted educational interventions for HCWs.

Main Methods:

• A cross-sectional, anonymous electronic survey was administered to HCWs in January 2022.
• The survey assessed awareness, knowledge, information sources, and perceptions related to the Omicron variant.
• A total of 940 HCWs completed the survey, with good knowledge/perception defined as ≥80% correct answers.

Main Results:

• All participants were aware of the Omicron variant, but only 36.3% received formal training or discussions.
• A significant proportion of HCWs demonstrated limited knowledge (24.3%) and perception (20.6%) regarding Omicron.
• HCWs who participated in training showed significantly higher knowledge and perception scores (OR: 1.80).

Conclusions:

• Despite widespread awareness, HCWs exhibit suboptimal knowledge and perceptions of the SARS-CoV-2 Omicron variant.
• Formal training and educational discussions are strongly associated with improved HCW understanding of the Omicron variant.
• Continuous educational initiatives are essential to enhance HCW preparedness and response to emerging SARS-CoV-2 variants.