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Updated: Sep 29, 2025

Development and Validation of a Quantitative PCR Method for Equid Herpesvirus-2 Diagnostics in Respiratory Fluids
Published on: March 17, 2016
Inflammatory Response and Electrocardiographic Examination in Horses Vaccinated against Equine Herpesvirus (Ehv-1)
Vito Biondi1, Alessandra Landi2, Michela Pugliese1
1Department of Veterinary Sciences, University of Messina, 98168 Messina, Italy.
Abstract:
This study aimed to evaluate possible abnormalities in electrocardiographic findings, and changes in cardiac troponin I (cTnI) and inflammatory biomarkers (serum amyloid A (SAA) and C-reactive protein (CRP)) after inactivated herpesvirus vaccine administration. Eighteen healthy horses were included. All animals were vaccinated with Pneumoequine® (Merial, France) according to the protocol provided by the manufacturer. They were evaluated 1 day before the first dose of vaccination (D0), and 7 days (D1) and 14 days (D2) afterwards. At D0, D1, and D2, a blood sample was taken for the evaluation of SAA, cTnI, and CRP. An electrocardiographic examination was also performed. The data obtained suggested the possible involvement of the myocardium following vaccination against herpesvirus 1, mostly related to an inflammatory response.
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