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Research into Morphofunctional Characteristics of Erythrocytes in COVID-19 Patients
Victor Revin1, Larisa Balykova1, Sergey Pinyaev1
1Federal State Budgetary Educational Institution of Higher Education, Ogarev Mordovia State University, 430005 Saransk, Russia.
Abstract:
In this paper, the erythrocytes of healthy donors and people with a confirmed diagnosis of COVID-19 were tested by Raman spectroscopy and laser interference microscopy. We argue that erythrocytes (red blood cells) in COVID-19 patients have an irregular shape, and their morphometric characteristics are impaired in comparison to healthy red blood cells. Raman spectroscopy also allows us to detect a decreased oxygen transport function of these erythrocytes. The combination of these methods-Raman spectroscopy and laser interference microscopy-is a highly effective method for the diagnosis of SARS-CoV-2.
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