Related Experiment Video
Updated: Sep 29, 2025

Generation of Cancer Cell Clones to Visualize Telomeric Repeat-containing RNA TERRA Expressed from a Single Telomere in Living Cells
Published on: January 17, 2019
Telomeric Repeat-Containing RNA (TERRA): A Review of the Literature and First Assessment in Cutaneous T-Cell
Alain Chebly1,2, Joana Ropio1,3,4, Lyla Baldasseroni1
1BoRdeaux Institute of Oncology (BRIC), UMR1312, INSERM, University of Bordeaux, 146 Rue Leo Saignat, 33076 Bordeaux, France.
Abstract:
Telomeric Repeat-containing RNA (TERRA) are long non-coding RNAs transcribed from telomeric DNA sequences from multiple chromosome ends. Major research efforts have been made to understand TERRA roles and functions in several physiological and pathological processes. We summarize herein available data regarding TERRA's roles in human cells and we report the first investigation in cutaneous T-cells lymphomas (CTCL) using real-time PCR. Among the TERRA analysed, our data suggest a particular role for TERRA 16p downregulation and TERRA 11q upregulation in CTCL lymphomagenesis.
More Related Videos
08:26Semi-quantitative Detection of RNA-dependent RNA Polymerase Activity of Human Telomerase Reverse Transcriptase Protein
Published on: June 12, 2018
08:34Utilizing Murine Inducible Telomerase Alleles in the Studies of Tissue Degeneration/Regeneration and Cancer
Published on: April 13, 2015
Related Concept Videos
Telomeres and Telomerase
Non-LTR Retrotransposons
Replicative Cell Senescence
lncRNA - Long Non-coding RNAs