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COVID-19 Infection Complicated by Disseminated Intravascular Coagulation during Pregnancy-Two Cases Report

Małgorzata Skalska-Świstek1, Hubert Huras1, Andrzej Piotr Jaworowski1

  • 1Department of Obstetrics and Perinatology, Medical College, Jagiellonian University, 23 Kopernika Str., 31-501 Krakow, Poland.

Diagnostics (Basel, Switzerland)
|March 25, 2022
PubMed

Insights

Disseminated intravascular coagulation (DIC) is a severe obstetric complication linked to SARS-CoV-2 infection. Close monitoring of coagulation parameters and timely delivery are crucial for managing DIC in pregnant patients.

Area of Science:

  • Obstetrics
  • Hematology
  • Infectious Diseases

Background:

  • Coagulopathies represent significant obstetric complications during pregnancy, childbirth, and puerperium.
  • Disseminated intravascular coagulation (DIC) is a complex hemostatic disorder characterized by systemic coagulation activation and inflammatory cell involvement.

Observation:

  • DIC syndrome was identified in pregnant patients with SARS-CoV-2 infection.
  • The clinical course and literature suggest a link between SARS-CoV-2 and DIC in pregnancy.

Findings:

  • Close monitoring of coagulation system laboratory parameters is essential.
  • Fetal well-being requires diligent observation throughout pregnancy complicated by DIC.

Implications:

  • Prompt delivery and intensive therapy are advised in cases of acute DIC development.
  • Managing DIC in SARS-CoV-2-infected pregnancies necessitates a multidisciplinary approach focusing on coagulation status and fetal health.

Keywords:
COVID-19DICSARS-CoV-2childbirthcoagulopathiesdisseminated intravascular coagulation syndromepregnancy

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