Baseline Complete Blood Count and Chemistry Panel Profile from the Japan Environment and Children's Study (JECS)
Yu Taniguchi1, Shin Yamazaki1, Shoji F Nakayama1
1Japan Environment and Children's Study Programme Office, National Institute for Environmental Studies, Tsukuba 305-8506, Japan.
Insights
This study presents complete blood count and chemistry panel data for pregnant women in the Japan Environment and Children's Study (JECS). These findings offer essential reference values for maternal health during pregnancy.
Area of Science:
- Environmental Health
- Maternal Health
- Pediatric Health
Background:
- The Japan Environment and Children's Study (JECS) is a nationwide birth cohort study.
- It investigates environmental factors impacting children's health and development.
- This study focuses on data from pregnant women within the JECS cohort.
Purpose of the Study:
- To summarize complete blood count (CBC) and chemistry panel statistical data.
- To provide reference values for pregnant women enrolled in the JECS.
- To support future research on environmental influences on maternal and child health.
Main Methods:
- Analysis of CBC and chemistry panel data from pregnant women in JECS.
- Inclusion of data from up to 58,056 mothers.
- Data collected during the first (≤13 weeks) and second (22-27 weeks) trimesters of gestation.
Main Results:
- Presents mean (SD) values for CBC parameters in the first trimester (e.g., WBC, RBC, hemoglobin, hematocrit, platelets).
- Provides first-trimester mean (SD) values for chemistry panels (e.g., HbA1c, total cholesterol, triglycerides, protein, albumin).
- Reports second-trimester mean (SD) values for key chemistry markers (e.g., cholesterol, triglycerides, protein, albumin).
Conclusions:
- The presented data provide valuable statistical benchmarks.
- These reference values are crucial for ongoing and future JECS research.
- The findings contribute to understanding maternal physiological changes during pregnancy.
Background:
The Japan Environment and Children's Study (JECS) is a nationwide birth cohort study of environmental factors affecting children's health and development. We summarize the complete blood count and chemistry panel statistical data from pregnant women enrolled in JECS.
Methods:
Statistical data of up to 58,056 mother's sample in their first (gestational age ≤ 13 weeks) and second trimester (22-27 weeks) were calculated.
Results:
Mean (SD) values in the first trimester were: white blood cell count, 7866 (1906)/μL; red blood cell count, 417 (33) 104/μL; hemoglobin, 12.4 (1.0) g/dL; hematocrit, 37.1 (2.6)%; mean corpuscular volume, 89.2 (4.7) fL; mean corpuscular hemoglobin, 29.8 (1.9) pg; mean corpuscular hemoglobin concentration, 33.3 (0.9)%; platelet count, 24.8 (5.2) 104/μL; HbA1c, 5.26 (0.26)%; total cholesterol, 181 (28) mg/dL; low density lipoprotein cholesterol, 95 (23) mg/dL; high density lipoprotein cholesterol, 73 (13) mg/dL; free cholesterol, 41 (7) mg/dL; triglycerides, 109 (47) mg/dL; total protein, 6.9 (0.4) g/dL; and albumin, 4.1 (0.2) g/dL. Mean values (SD) in the second trimester were: total cholesterol, 246 (38) mg/dL; free cholesterol, 61 (9) mg/dL; triglycerides, 183 (70) mg/dL; total protein, 6.5 (0.4) g/dL; and albumin, 3.6 (0.2) g/dL.
Conclusions:
These data will be useful for future JECS studies.
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