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Clinical Implementational and Site-Specific Workflows for a 1.5T MR-Linac.
David A P Dunkerley1, Daniel E Hyer1, Jeffrey E Snyder1
1Department of Radiation Oncology, University of Iowa Health Care, Iowa City, IA 52242, USA.
Journal of Clinical Medicine
|March 25, 2022
Summary
MR-guided adaptive radiotherapy (MRgART) enhances cancer treatment using advanced imaging. This study details practical workflows and considerations for implementing MRgART across various anatomical sites for optimal patient care.
Area of Science:
- Medical Physics
- Radiation Oncology
- Oncology
Background:
- MR-guided adaptive radiotherapy (MRgART) leverages advanced imaging during treatment.
- This technology presents unique challenges based on anatomical site and tissue changes.
- Implementing MRgART requires careful consideration of patient selection, planning, and adaptation criteria.
Purpose of the Study:
- To present an institution's experience developing an MRgART program.
- To outline practical workflows and considerations for MRgART implementation.
- To detail the treatment of the first 234 patients using a 1.5T MR-linac.
Main Methods:
- Development of an MR-guided adaptive radiotherapy program.
- Treatment of 234 patients on a 1.5T MR-linac.
- Exploration of patient selection, immobilization, and adaptive planning strategies.
Main Results:
- Successful implementation of MRgART across diverse anatomical sites.
- Established practical treatment workflows and imaging guidelines.
- Gained experience in patient immobilization and adaptive plan utilization.
Conclusions:
- MRgART offers significant benefits for cancer patients.
- Careful planning and adaptation are crucial for successful MRgART implementation.
- This experience provides a foundation for broader MRgART program development.

