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Sleep-related Breathing Disorders in Children with Asthma: Impact on Asthma Control
Nurbanu Bilgin1, Sebnem Ozdogan2, Aysenur Kaya3
1Department of Pediatrics, University of Health Sciences, Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.
Insights
Uncontrolled persistent asthma in children is linked to sleep-related breathing disorders. Allergic rhinitis, habitual snoring, and poor asthma control are key risk factors.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
Background:
- Persistent asthma affects a significant pediatric population.
- Sleep-related breathing disorders (SRBD) are common in children.
- Asthma control and SRBD in children require further investigation.
Purpose of the Study:
- To determine the frequency of SRBD in children with persistent asthma.
- To explore the association between asthma control and SRBD in this population.
Main Methods:
- A comparative cross-sectional study was conducted.
- 120 children (aged 4-11) with persistent asthma were enrolled.
- Pediatric sleep questionnaire and childhood asthma control tests were administered.
Main Results:
- The prevalence of habitual snoring was 20.8% and SRBD was 29.2%.
- SRBD was significantly more prevalent in children with uncontrolled asthma (p <0.001).
- Allergic rhinitis, habitual snoring, and low asthma control scores independently predicted SRBD.
Conclusions:
- Uncontrolled asthma is significantly associated with SRBD in children.
- Allergic rhinitis, habitual snoring, and low asthma control are identified as risk factors for SRBD.
- These findings highlight the importance of assessing sleep in asthmatic children.
Objective:
To investigate the frequency of sleep-related breathing disorder and the relationship between asthma control and sleep-related breathing disorder in children with persistent asthma.
Study Design:
Comparative cross-sectional study.
Place And Duration Of Study:
University of Health Sciences, Hamidiye Etfal Training and Research Hospital, Istanbul/Turkey, from January 2019 to June 2019.
Methodology:
Children aged 4-11 years with persistent asthma were included. At enrollment, socio-demographic and asthmatic characteristics were investigated, and pediatric sleep questionnaire and childhood asthma control tests were administered.
Results:
Out of 120 patients, 75 (62.5%) were males and 45 (37%) females. According to GINA guidelines, asthma was well controlled in 23.3% children, partially controlled in 50.8% children and uncontrolled in 25.8% children. The frequency of habitual snoring was reported as 20.8% and the frequency of sleep-related breathing disorder was 29.2%. The prevalence of sleep-related breathing disorders was significantly higher in the uncontrolled asthma group (p <0.001). Significant-independent efficacy of physician-diagnosed allergic rhinitis, habitual snoring, and low asthma control test scores was observed in predicting sleep-related breathing disorders in multivariate logistic regression model (p <0.001).
Conclusion:
Uncontrolled asthma is associated with sleep-related disordered breathing. The authors suggest that allergic rhinitis, habitual snoring, and low asthma control test scores are important risk factors for sleep-related breathing disorders in children with persistent asthma.
Key Words:
Asthma, Asthma control test, Allergic rhinitis, Habitual snoring, Pediatric sleep questionnaire, Sleep-related breathing disorder.
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