Splenectomy during Gastric Cancer Surgery versus Splenectomy during Extra-gastric Abdominal Cancer Surgery

Area of Science:

• Oncology
• Surgical Oncology
• Gastroenterology

Background:

• Splenectomy is a surgical procedure involving the removal of the spleen.
• Gastric cancer and other intra-abdominal malignancies necessitate complex surgical interventions.
• Understanding the implications of concomitant splenectomy is crucial for optimizing patient outcomes.

Purpose of the Study:

• To compare clinicopathological differences between splenectomy performed during gastric cancer surgery versus extra-gastric abdominal cancer surgery.
• To identify specific outcomes associated with each surgical scenario.

Main Methods:

• Retrospective observational study of 45 patients undergoing concomitant splenectomy.
• Patients were divided into two groups: gastric cancer surgery and extra-gastric abdominal cancer surgery.
• Clinicopathological characteristics and outcomes were analyzed using appropriate statistical tests (p<0.05).

Main Results:

• Splenectomy during gastric cancer surgery (30 patients) required more erythrocyte suspension (p=0.040).
• Patients undergoing splenectomy with extra-gastric cancer surgery experienced longer hospital stays (p=0.036) and higher overall morbidity (p=0.011).
• Elective surgery was performed in 95.6% of patients.

Conclusions:

• Splenectomy during gastric cancer surgery is more demanding, necessitating greater blood transfusion support.
• Despite being more demanding, splenectomy in gastric cancer patients showed a trend towards lower morbidity.
• Concomitant splenectomy in extra-gastric cancer surgery is associated with increased length of hospital stay and higher morbidity.