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An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function
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Long term digestive outcome of œsophageal atresia

Aumar Madeleine1, Nicolas Audrey1, Sfeir Rony1

  • 1Univ. Lille, Reference Centre for rare œsophageal diseases, CHU Lille, U 1286 INFINITE, F59000, Lille, France.

Best Practice & Research. Clinical Gastroenterology
|March 25, 2022
PubMed

Insights

Esophageal atresia, a congenital esophagus defect, has low mortality but high long-term morbidity. Adults face lifelong digestive issues, impacting quality of life and requiring ongoing medical surveillance.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Neonatology

Background:

  • Esophageal atresia is a rare congenital malformation characterized by esophageal discontinuity.
  • While surgical repair is often successful in infancy, significant long-term morbidity persists.

Purpose of the Study:

  • To highlight the persistent digestive and nutritional morbidities in adults born with esophageal atresia.
  • To emphasize the need for lifelong follow-up due to long-term complications.

Main Methods:

  • Review of long-term outcomes in adult patients with a history of esophageal atresia.
  • Analysis of common digestive and nutritional sequelae.

Main Results:

  • Adults with esophageal atresia frequently experience dysphagia, gastro-esophageal reflux, and esophageal dysmotility.
  • These conditions lead to significant nutritional challenges and reduced quality of life.
  • Increased risks of Barrett's esophagus, esophageal cancer, anastomotic stenosis, and eosinophilic esophagitis are noted.

Conclusions:

  • Despite advances in neonatal surgery, esophageal atresia survivors require lifelong multidisciplinary follow-up.
  • Transition to adult care is crucial for managing chronic digestive issues and cancer surveillance.

Keywords:
AdolescentBarrett œsophagusDysphagiaEosinophilic œsophagitisGastro-œsophageal refluxNeonatal surgeryTransitionŒsophageal atresiaœsophageal cancerœsophageal dysmotility

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