[Development of catabolic repression during Escherichia coli growth on a carbohydrate mixture]

During the cell growth with mixture of three sources of carbon (mannit-arabinose-glycerol, glucose-sorbite-glycerol, glucose-sorbite-galactose) the components of the mixture have been found to be utilized in series. After using up the first, the repression is eliminated unselectively in utilization both the second and the third. Then after the lag-period the utilization repression of the third carbon source by the second one occurs. The phenomenon of "remaining repression" consisting in that at the cell growth with mixture of mannite and sorbite after using up the first carbohydrate the cells cannot start utilizing the second has been described.