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Analysis of choroidal vascularity index in multiple sclerosis patients without optic neuritis attack
Emine Temel1, Nazife Aşıkgarip1, Yusuf Koçak1
1Department of Ophthalmology, Kırşehir Ahi Evran Training and Research Hospital, Turkey.
Background:
To evaluate the choroidal structural changes in multiple sclerosis (MS) patients without previous optic neuritis (ON) attacks.
Methods:
Forty eyes of 20 MS patients without a history of ON and 40 eyes of 20 age-matched healthy volunteers were included in this study. The choroidal thickness (CT) was measured at three points; subfoveal, 1500 µm nasal to the fovea, and 1500 µm temporal to the fovea. Choroidal area (CA), luminal area (LA), and choroidal vascularity index (CVI) were calculated using ImageJ.
Results:
The mean subfoveal, nasal and temporal CT were decreased in MS patients compared to controls (for all, p < 0.001). The mean LA was 0.572 ± 0.113 mm2 in MS group, and 0.729 ± 0.188 mm2 in controls (p = 0.002). The mean CVI was decreased in the MS group (69.38% ± 4.87) in comparison to the controls (73.41% ± 5.18) (p = 0.034).
Conclusion:
The current study demonstrated significant anatomical alterations of the choroid in the eyes of patients with MS.
