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Updated: Sep 29, 2025

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
Non-diseased aortic mural thrombus presenting with acute limb ischaemia
Ali Khalil1, John J Kanitra2, David Lorelli3
1School of Medicine, St George's University, St George's, Grenada.
A rare case of thoracic aortic mural thrombus (AMT) in a healthy aorta causing acute limb ischemia was successfully treated with anticoagulation. The thrombus resolved within five months, highlighting effective medical management for this uncommon condition.
Area of Science:
- Cardiovascular Medicine
- Vascular Surgery
- Diagnostic Imaging
Background:
- Thoracic aortic mural thrombus (AMT) is uncommon, particularly in non-atherosclerotic and non-aneurysmal aortas.
- Acute limb ischemia is a rare presentation for AMT in a healthy aorta.
- Underlying hypercoagulable disorders are often associated with aortic thrombus formation.
Observation:
- A patient presented with acute limb ischemia secondary to a thoracic aortic mural thrombus.
- The aorta was assessed as non-atherosclerotic and non-aneurysmal.
- No underlying hypercoagulable disorder was identified in the patient.
Findings:
- The thoracic aortic mural thrombus was successfully managed with anticoagulation therapy.
- Follow-up CT scans at 5 months showed complete resolution of the thrombus.
- This case demonstrates the efficacy of medical management for AMT in a non-diseased aorta.
Implications:
- Successful anticoagulation offers a less invasive treatment option for selected cases of thoracic aortic mural thrombus.
- This case contributes to the limited literature on managing AMT in the absence of aortic disease or hypercoagulability.
- Further research into the etiology and optimal management strategies for non-atherosclerotic AMT is warranted.
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