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Updated: Sep 29, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Right atrium to left ventricle puncture for VT ablation in patients with mechanical aortic and mitral valves: A
1Electrophysiology Section, Division of Cardiovascular, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Abstract:
In patients with mechanical valves in the aortic and mitral positions, percutaneous access to the left ventricle (LV) for catheter ablation (CA) of ventricular tachycardia (VT) is challenging. We have recently described a novel percutaneous trans-right atrial (RA) access to the LV via a femoral venous approach for CA of VT in patients with mechanical aortic and mitral valves. With this approach, an iatrogenic Gerbode-type of ventricular septal defect is created with direct puncture of the inferior and medial aspect of the RA anatomically adjacent to the inferior-septal LV. The technique involves the use of steerable sheaths, dedicated radiofrequency wires, and intracardiac echocardiography guidance. The procedure has been documented feasible and safe in a series of consecutive patients with aortic and mitral mechanical valves and VT related to LV substrate. In this study, the procedural details of this novel approach are described in a step-by-step fashion.
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