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Teeth

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...

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Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

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Published on: March 29, 2018

Microcephaly as a risk factor for dental alterations: A case-control study.

Patrícia Nóbrega Gomes¹, Isabelita Duarte Azevedo¹, Beatriz Aguiar do Amaral¹

¹Department of Dentistry, School of Dentistry, Federal University of Rio Grande do Norte, Natal, Brazil.

|March 25, 2022

Summary

Microcephaly significantly increases the risk of delayed tooth eruption and enamel defects in children. This condition impacts dental development, affecting tooth eruption sequence and enamel quality in primary teeth.

Keywords:

congenital infections disturbances in dental development microcephaly

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Area of Science:

Pediatric Dentistry
Developmental Pediatrics
Oral Health

Background:

Microcephaly is a condition characterized by an abnormally small head circumference.
Dental development can be affected by various congenital and developmental disorders.
Understanding the oral health implications of microcephaly is crucial for early intervention.

Purpose of the Study:

To investigate if microcephaly is a risk factor for altered tooth eruption.
To assess the association between microcephaly and developmental defects of enamel.
To determine the impact of microcephaly on the chronology and sequence of primary tooth eruption.

Main Methods:

A case-control study involving 81 children aged 30-36 months.
Comparison between 41 children with microcephaly and 40 normoreactive children.
Oral clinical examination to evaluate tooth eruption patterns and enamel defects.

Main Results:

Microcephaly showed a significant association with delayed tooth eruption (p < 0.001).
Alterations in tooth eruption sequence and enamel defects were significantly linked to microcephaly (p < 0.001).
Low birthweight and prematurity were also associated with dental anomalies.

Conclusions:

Microcephaly is confirmed as a risk factor for dental developmental issues.
The study highlights significant alterations in tooth eruption and enamel formation in children with microcephaly.
These findings underscore the importance of monitoring oral health in children with microcephaly.