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Updated: Sep 29, 2025

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Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
Published on: December 23, 2022
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Cerebral Fat Embolism via a Patent Foramen Ovale
Megan A Cibulas1, Eddy H Carrillo2, Seong K Lee2
1Department of Surgery, 3932Memorial Healthcare System General Surgery Residency Program, Hollywood, FL, USA.
The American Surgeon
|March 25, 2022
Summary
Fat embolism syndrome (FES) can occur after fractures and surgery. This case shows a young man recovering fully from cerebral fat embolism after a femur fracture, highlighting the importance of recognizing this condition.
Area of Science:
- Trauma Surgery
- Neurology
- Cardiology
Background:
- Fat embolism syndrome (FES) is a serious complication often following long bone fractures or orthopedic surgery.
- Early identification and management are crucial for patient outcomes.
Observation:
- A 19-year-old male sustained multiple injuries, including a right femoral shaft fracture, after a motor vehicle collision.
- Following intramedullary nailing of the femur, the patient developed aphasia, tachycardia, and hypoxemia.
- Brain MRI revealed acute ischemic infarcts in a characteristic starfield pattern, suggestive of cerebral fat embolism.
Findings:
- The patient was diagnosed with fat embolism syndrome (FES) with cerebral involvement (CFE).
- An echocardiogram identified a patent foramen ovale (PFO), a potential contributing factor.
- Supportive care led to significant clinical improvement and eventual symptom resolution.
Implications:
- This case underscores the potential for complete neurologic recovery from CFE with timely supportive management.
- The presence of a PFO may warrant consideration in patients with FES, particularly those with paradoxical embolism concerns.
- Prompt recognition and multidisciplinary care are vital for managing FES and improving patient prognosis.
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