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Intracarotid Cancer Cell Injection to Produce Mouse Models of Brain Metastasis

Intracarotid Cancer Cell Injection to Produce Mouse Models of Brain Metastasis

Published on: February 8, 2017

Primary Breast Neuroendocrine Tumor.

V Morgan Jones¹, Ashley Cairns¹, Akiko Chiba¹

¹Department of Surgery, 12279Wake Forest University School of Medicine, Winston-Salem, NC, USA.

The American Surgeon

|March 25, 2022

Summary

Breast primary neuroendocrine tumors (BNETs) are rare cancers. This case study discusses diagnosis and treatment protocols for BNETs, which lack standardized management due to their rarity.

Keywords:

Breast surgical oncology

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Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

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Area of Science:

Oncology
Endocrinology

Background:

Breast primary neuroendocrine tumors (BNETs) constitute less than 1% of breast cancer diagnoses.
Detection typically involves physical examinations and mammography.

Observation:

Diagnosis requires excluding other primary neuroendocrine tumor sources (e.g., pancreatic, lung, appendix).
Histopathology shows positive staining for chromogranin A and/or synaptophysin.

Findings:

Standardized treatment protocols for BNETs are lacking due to rarity.
Current treatments are based on limited case reports and anecdotal evidence.

Implications:

This case highlights the diagnostic challenges and therapeutic uncertainties in managing BNETs.
Further research is needed to establish standardized treatment guidelines for BNETs.