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Published on: April 21, 2023
Thyroid Nodules in Children With Familial Adenomatous Polyposis
Jessica R Smith1, Junne Kamihara2, Alanna J Church3
1Thyroid Center, Boston Children's Hospital, Boston, Massachusetts, USA.
Introduction:
Ultrasound screening for thyroid cancer is recommended in familial adenomatous polyposis (FAP). This study investigated the prevalence of thyroid neoplasia in children with FAP.
Methods:
Cross-sectional study of children with FAP at an academic hospital. Clinical and ultrasound data were analyzed for the prevalence of thyroid nodules and cancer.
Results:
Of 37 children with FAP, 8 (22%) had thyroid nodules and 2 (5%) had thyroid cancer. Nodules (30%) and cancer (9%) were more common among female subjects and rare among male subjects.
Discussion:
Thyroid ultrasound screening in adolescence may benefit female subjects with FAP but has limited utility in male subjects.
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