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Agreement between 2 SS-OCT biometry devices.

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  • 1From the Department of Ophthalmology, Princess Alexandra Hospital, Woolloongabba, Brisbane, Queensland, Australia (McLintock, Seo); Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia (McLintock); Contact Lens and Visual Optics Laboratory, Centre for Vision and Eye Research, School of Optometry and Vision Science, Queensland University of Technology, Kelvin Grove, Queensland, Australia (Niyazmand); Lions Eye Institute, Perth, Western Australia, Australia (Barrett); Centre for Ophthalmology and Visual Science, University of Western Australia, Perth, Western Australia, Australia (Barrett); Sir Charles Gairdner Hospital, Perth, Western Australia, Australia (Barrett); Centre for Ophthalmology and Visual Science (incorporating Lions Eye Institute), University of Western Australia, Perth, Australia (Nilagiri); Department of Ophthalmology, University of Auckland, Auckland, New Zealand (McKelvie).

Journal of Cataract and Refractive Surgery
|March 25, 2022
PubMed
Summary

The Anterion and IOLMaster 700 devices show significant differences in posterior and total keratometry, indicating they are not interchangeable for corneal measurements. This impacts refractive outcomes.

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Optometry

Background:

  • Accurate biometry is crucial for intraocular lens calculations.
  • Swept-source optical coherence tomography (SS-OCT) devices offer advanced biometry capabilities.
  • Comparing new devices like Anterion with established ones like IOLMaster 700 is essential for clinical adoption.

Purpose of the Study:

  • To evaluate the agreement between two SS-OCT biometry devices: Anterion and IOLMaster 700.
  • To determine if differences in measurements between devices are clinically significant for refractive surgery planning.

Main Methods:

  • A prospective comparative study was conducted at a tertiary referral center.
  • Bland-Altman analysis assessed agreement for various ocular parameters, including keratometry (anterior, posterior, total), lens thickness, anterior chamber depth, central corneal thickness, white-to-white distance, and axial length.
  • Clinical significance was defined as a potential alteration of 0.25 diopters or more in spherical refractive outcome.

Main Results:

  • Statistically significant differences were observed for anterior, posterior, and total corneal keratometry (K1, K2, Km) between the Anterion and IOLMaster 700.
  • The mean differences for posterior and total keratometry were clinically significant.
  • While statistically significant differences were found for lens thickness, anterior chamber depth, central corneal thickness, and white-to-white distance, they were not clinically significant. No significant difference was found for axial length.

Conclusions:

  • The Anterion and IOLMaster 700 exhibit statistically and clinically significant discrepancies in posterior and total keratometry.
  • Posterior and total corneal measurements from these two devices are not interchangeable.
  • Clinicians should be aware of these differences when planning refractive surgery and selecting biometry devices.