Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

95
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
95
Spongy Bone01:09

Spongy Bone

5.7K
All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
5.7K
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

142
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
142
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

63
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
63
Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

46
Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
46
Compact Bone01:27

Compact Bone

13.3K
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
13.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multimorbidity patterns among fragility fracture patients aged 50 + years in China and the US.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2026
Same author

Machine learning derived abdominal aortic calcification is associated with physical frailty in community-dwelling adults: the UK Biobank Imaging Study.

GeroScience·2026
Same author

Fracture risk thresholds for majority incident fracture identification: A registry-based cohort analysis.

Bone·2026
Same author

Automated abdominal aortic calcification, muscle health and incident falls: the UK Biobank Imaging Study.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2026
Same author

Forearm BMD predicts fracture independently of FRAX.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2026
Same author

Prevalent vertebral fracture (PVFx) and abdominal aortic calcification (AAC) independently predict incident atherosclerotic cardiovascular disease (ASCVD) events in older men.

Bone·2026

Related Experiment Video

Updated: Sep 29, 2025

Author Spotlight: Enhancing Rheumatoid Arthritis Research Through HR-pQCT Imaging Analysis
06:31

Author Spotlight: Enhancing Rheumatoid Arthritis Research Through HR-pQCT Imaging Analysis

Published on: October 6, 2023

2.5K

Trabecular Bone Score in Rheumatic Disease.

Ceri Richards1,2, William D Leslie3,4

  • 1Department of Internal Medicine, University of Manitoba, Winnipeg, MB, Canada. ceri.richards@umanitoba.ca.

Current Rheumatology Reports
|March 25, 2022
PubMed
Summary
This summary is machine-generated.

Trabecular bone score (TBS) is lower in rheumatic disease patients and predicts fractures. This bone texture measure aids fracture risk assessment in conditions like ankylosing spondylitis and rheumatoid arthritis.

Keywords:
Dual-energy x-ray absorptiometryFractureFracture risk assessmentOsteoporosisRheumatic diseaseTrabecular bone score

More Related Videos

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness
08:52

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness

Published on: March 18, 2022

3.1K
Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model
06:59

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model

Published on: September 8, 2023

2.8K

Related Experiment Videos

Last Updated: Sep 29, 2025

Author Spotlight: Enhancing Rheumatoid Arthritis Research Through HR-pQCT Imaging Analysis
06:31

Author Spotlight: Enhancing Rheumatoid Arthritis Research Through HR-pQCT Imaging Analysis

Published on: October 6, 2023

2.5K
Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness
08:52

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness

Published on: March 18, 2022

3.1K
Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model
06:59

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model

Published on: September 8, 2023

2.8K

Area of Science:

  • Rheumatology
  • Osteoporosis Research
  • Medical Imaging Analysis

Background:

  • Rheumatic diseases elevate the risk of low bone mass and osteoporotic fractures.
  • Trabecular bone score (TBS) is a novel metric derived from DXA, assessing bone texture.
  • TBS independently predicts fracture risk.

Purpose of the Study:

  • To review the significance of TBS in rheumatic diseases.
  • To evaluate TBS's role in fracture prediction within this patient population.

Main Methods:

  • Review of cross-sectional and longitudinal studies on TBS in rheumatic diseases.
  • Analysis of TBS associations with prevalent and incident fractures.
  • Examination of TBS in specific rheumatic conditions like ankylosing spondylitis.

Main Results:

  • Patients with rheumatic diseases consistently show lower TBS compared to controls.
  • TBS is associated with and predicts prevalent fractures.
  • Longitudinal studies indicate TBS predicts incident fractures.
  • TBS degradation correlates with disease activity in ankylosing spondylitis, systemic sclerosis, and rheumatoid arthritis.
  • Glucocorticoid use is linked to lower TBS and predicts fractures in rheumatic patients.

Conclusions:

  • TBS is a valuable tool for assessing bone health and fracture risk in rheumatic diseases.
  • TBS offers insights into fracture prediction beyond traditional bone mineral density.
  • Further research is warranted to integrate TBS into clinical management strategies for rheumatic conditions.