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Published on: December 4, 2015
Swine Norovirus: Past, Present, and Future
Lara Cavicchio1, Andrea Laconi2, Alessandra Piccirillo2
1Diagnostic Virology Laboratory, Istituto Zooprofilattico Sperimentale delle Venezie (IZSVE), Viale dell'Università 10, Legnaro, 35020 Padua, Italy.
Swine norovirus is globally distributed and can infect humans, posing a zoonotic risk. This review examines swine norovirus prevalence, genotypes, and detection challenges.
Area of Science:
- Veterinary Virology
- Public Health Virology
- Molecular Epidemiology
Background:
- Norovirus causes significant global gastroenteritis burden in humans.
- Swine norovirus has been detected worldwide since the 1990s.
- The presence of human-associated norovirus genotypes in swine raises zoonotic concerns.
Purpose of the Study:
- To review the geographic distribution and prevalence of swine norovirus.
- To characterize norovirus genotypes found in swine populations.
- To identify challenges in detecting and characterizing swine noroviruses.
Main Methods:
- Systematic literature review of published studies on swine norovirus.
- Analysis of geographic distribution, detection years, and prevalence data.
- Genotype characterization and discussion of detection bottlenecks.
Main Results:
- Swine norovirus is geographically widespread, with varying prevalence across continents and production groups.
- Genotype characterization reveals both swine-specific and potentially zoonotic strains, like GII.4.
- Detection and characterization are hindered by technical and logistical challenges.
Conclusions:
- Swine can act as a reservoir for noroviruses with zoonotic potential.
- Further research is needed to understand transmission dynamics and improve surveillance.
- Addressing detection bottlenecks is crucial for effective monitoring and control.
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