Oral immune-mediated disorders with malignant potential/association: An overview

Area of Science:

• Oral Medicine
• Immunology
• Oncology

Background:

• Oral immune-mediated disorders stem from dysregulated immune responses.
• These conditions can range from benign to those with malignant potential or association.

Purpose of the Study:

• To provide an overview of select oral immune-mediated disorders.
• To highlight their association with or potential for malignancy.

Main Methods:

• Literature review and synthesis of existing research.
• Focus on specific oral diseases including oral lichen planus, Sjogren's syndrome, and others.

Main Results:

• Identified several oral immune-mediated diseases with varying degrees of malignant association.
• Highlighted the increased morbidity and mortality linked to these conditions.

Conclusions:

• Understanding these disorders is crucial for managing associated malignancy risks.
• Early recognition and management can mitigate severe health outcomes.