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COVID-19 Aortitis: A Review of Published Cases
Falah Abu Hassan1, Minas Abu Alhalawa2, Yacoub Majdoubeh3
1Internal Medicine, Texas Tech University Health Sciences Center, Amarillo, USA.
Insights
This review explores aortitis, a rare complication of Coronavirus disease 2019 (COVID-19). Four male patients with COVID-19-associated aortitis recovered well with conservative treatment.
Area of Science:
- Cardiology
- Infectious Diseases
- Vascular Surgery
Background:
- Coronavirus disease 2019 (COVID-19) presents with diverse clinical manifestations and complications.
- Aortitis, an inflammation of the aorta, is an under-recognized pathology linked to COVID-19 infections.
Purpose of the Study:
- To review and synthesize existing case reports on aortitis in adult patients diagnosed with COVID-19.
- To understand the clinical characteristics, management, and outcomes of COVID-19-associated aortitis.
Main Methods:
- A systematic literature search was conducted across major databases: PubMed/Medline, Web of Science, Google Scholar, and Scopus.
- The review focused on case series and case reports detailing adult patients with concurrent diagnoses of aortitis and COVID-19.
Main Results:
- Four published case reports met the inclusion criteria.
- The affected patients were exclusively male, with a mean age of 69 years.
- A significant majority (75%) had no prior comorbidities; all patients experienced positive outcomes with conservative management.
Conclusions:
- Aortitis is a potential, albeit rare, complication of COVID-19.
- Early identification and conservative treatment strategies appear effective for COVID-19-related aortitis, leading to favorable patient outcomes.
Abstract:
Coronavirus disease 2019 (COVID-19) has a myriad of different presentations and various complications. Aortitis is one of the less explored pathologies associated with COVID-19 infections. In this review, we searched PubMed/Medline, Web of Science, Google Scholar, and Scopus for case series and case reports involving adults patients who presented with aortitis and COVID-19. We found and reviewed four published case reports of aortitis in a setting of COVID-19 infection. The mean age of the four adult patients was 69 ± 1.732 years (range = 63-71 years), and all patients were males. Most of the patients (75%) did not have any preexisting comorbidities. All patients were treated conservatively and recovered with excellent outcomes.
