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Published on: December 18, 2010
Listerial Spontaneous Bacterial Peritonitis
Samira Samant1, Bradley Uyemura1, Pandit Sarbagya1
1Internal Medicine, Medical College of Wisconsin, Milwaukee, USA.
Abstract:
Spontaneous bacterial peritonitis (SBP) is a severe complication of ascites often seen in advanced hepatic disease that is most commonly caused by Gram-negative bacilli. Here, we report a rare case of Listeria monocytogenes SBP, diagnosed by peritoneal fluid culture and responsive to ampicillin, in a patient with portal hypertension secondary to nodular regenerative hyperplasia. Because Listeria species are resistant to empiric SBP therapies and delays in treatment have been associated with increased mortality, they must be considered in high-risk patients.
Insights
Spontaneous bacterial peritonitis (SBP) is a severe complication of ascites. This case highlights a rare Listeria monocytogenes infection, emphasizing the need for consideration in high-risk patients.
Area of Science:
- Hepatology
- Infectious Diseases
- Microbiology
Background:
- Spontaneous bacterial peritonitis (SBP) is a serious complication in patients with advanced liver disease and ascites.
- It is typically caused by Gram-negative bacteria, and standard empiric treatments target these pathogens.
Observation:
- A rare case of SBP caused by Listeria monocytogenes was identified in a patient with portal hypertension.
- The patient's condition was secondary to nodular regenerative hyperplasia.
Findings:
- Diagnosis was confirmed through peritoneal fluid culture, identifying Listeria monocytogenes.
- The patient's SBP responded well to ampicillin treatment.
Implications:
- Listeria species are often resistant to common SBP empiric therapies.
- Prompt consideration and diagnosis of Listeria monocytogenes SBP are crucial in high-risk individuals to prevent mortality associated with treatment delays.
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