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Tofacitinib for Prurigo Nodularis: A Case Report
Changlan Peng1, Chunxiao Li2, Yingying Zhou1
1Department of Dermatology, Chengdu University of Traditional Chinese Medicine, Chengdu, People's Republic of China.
Purpose:
Despite recent advances in the treatment of prurigo nodularis, conventional treatment suffers from a dilemma of poor efficacy. The clinical use of Janus kinase (JAK) inhibitors in the treatment of Prurigo nodularis has rarely been explored.
Patients And Methods:
We present a case of prurigo nodularis successfully treated with, JAK inhibitor tofacitinib with no adverse effects.
Results:
This case report of successful treatment shows a good clinical efficacy of using JAK inhibitor tofacitinib in the treatment of prurigo nodularis. Cytokines may be an important cause of prurigo nodularis.
Conclusion:
JAK inhibitor tofacitinib may be a new option for the treatment of prurigo nodularis, especially for patients who have failed conventional treatment.
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