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Updated: Sep 28, 2025

Carotid Artery Infusions for Pharmacokinetic and Pharmacodynamic Analysis of Taxanes in Mice
Published on: October 27, 2014
[A strange case of wide QRS tachycardia during paclitaxel chemotherapy]
Tiziana Leopizzi1, Agnese Maria Fioretti2, Antonio Di Monaco3
1U.O.C. Cardiologia e UTIC, Ospedale "SS. Annunziata", Taranto.
Abstract:
We report the case of a 50-year-old female patient with breast cancer who, during preoperative workup, presented repeated wide QRS complex tachycardias, recorded by Holter ECG. She was immediately referred to a hub center for electrophysiological study where she was diagnosed with right ventricular outflow tract ventricular tachycardia and underwent catheter ablation. The chemotherapy with paclitaxel that the patient was receiving combined with psychological stress may have triggered the arrhythmias.
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