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Related Concept Videos

Salivary Glands and Saliva01:23

Salivary Glands and Saliva

1.0K
The salivary glands, of which there are three pairs known as the parotid, submandibular, and sublingual glands, play a crucial role in maintaining oral health and initiating the digestive process. Positioned near the ears, beneath the masseter muscle, the parotid glands secrete saliva into the oral cavity through the parotid duct of Stensen. Meanwhile, the submandibular glands, located on the floor of the mouth, secrete saliva through channels named submandibular ducts. The sublingual glands,...
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Exocrine Glands: Methods of Secretion01:08

Exocrine Glands: Methods of Secretion

5.0K
Exocrine glands are those that release their secretions through ducts. Based on their mode of secretion, they can be classified into merocrine, apocrine, and holocrine.
Merocrine Secretion
Merocrine secretion is the most common type of exocrine secretion. The secretions are enclosed in vesicles and moved to the cell's apical surface, where the contents are released by exocytosis. For example, mucous, a watery secretion rich in the glycoprotein mucin, is a merocrine secretion. The eccrine...
5.0K
Exocrine Glands: Types of Secretions01:13

Exocrine Glands: Types of Secretions

2.9K
Exocrine glands produce and release a variety of glandular products. Exocrine glands can be classified into serous, mucous, or mixed types based on their secretory products.
Serous glands produce watery secretions rich in digestive enzymes and proteins. The constituent cells of the serous gland have centrally located nuclei and eosinophilic secretory granules in the cytoplasm. The parotid gland is an example of a serous gland. It secretes saliva, which contains enzymes, such as lipases and...
2.9K
Oral Cavity01:11

Oral Cavity

1.6K
The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
1.6K
Exocrine Glands: Unicellular and Multicellular Glands01:29

Exocrine Glands: Unicellular and Multicellular Glands

23.5K
Exocrine glands are classified as unicellular and multicellular. The unicellular glands are scattered single cells, such as goblet cells, found in the mucous membranes of the small and large intestines. On the other hand, multicellular exocrine glands develop as secretory sheets, like the internal lining of the abdomen or chest. Such secretory sheets release their secretions directly into the lumen of these organs. In addition, some multicellular glands have deep-seated secretory units to...
23.5K
Accessory Organs01:31

Accessory Organs

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Accessory organs are those that participate in the digestion of food but do not come into direct contact with it like the mouth, stomach, or intestine do. Accessory organs secrete enzymes into the digestive tract to facilitate the breakdown of food.
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Related Experiment Video

Updated: Sep 28, 2025

Isolation of Salivary Epithelial Cells from Human Salivary Glands for In Vitro Growth as Salispheres or Monolayers
08:03

Isolation of Salivary Epithelial Cells from Human Salivary Glands for In Vitro Growth as Salispheres or Monolayers

Published on: July 15, 2019

9.2K

Salivary gland function, development, and regeneration.

Alejandro M Chibly1, Marit H Aure1, Vaishali N Patel1

  • 1Matrix and Morphogenesis Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.

Physiological Reviews
|March 28, 2022
PubMed
Summary
This summary is machine-generated.

Recent advances in OMICS research enhance our understanding of salivary gland development and regeneration. This knowledge guides the development of novel cell and gene therapies for salivary dysfunction.

Keywords:
exocrine secretiongene therapyprogenitor cellsalivary glandxerostomia

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Isolation of Mouse Salivary Gland Stem Cells
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Related Experiment Videos

Last Updated: Sep 28, 2025

Isolation of Salivary Epithelial Cells from Human Salivary Glands for In Vitro Growth as Salispheres or Monolayers
08:03

Isolation of Salivary Epithelial Cells from Human Salivary Glands for In Vitro Growth as Salispheres or Monolayers

Published on: July 15, 2019

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Genetic Modification and Recombination of Salivary Gland Organ Cultures
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Isolation of Mouse Salivary Gland Stem Cells
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Isolation of Mouse Salivary Gland Stem Cells

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Area of Science:

  • Regenerative Medicine
  • Oral Biology
  • Molecular Genetics

Background:

  • Salivary glands are crucial for oral and overall health, producing saliva essential for bodily functions.
  • Understanding salivary gland structure, function, and disease is key to developing effective regenerative therapies.
  • Recent OMICS advancements offer unprecedented insights into salivary gland biology.

Purpose of the Study:

  • To elucidate the cellular, molecular, and genetic mechanisms underlying salivary gland development and regeneration.
  • To identify key signaling pathways and progenitor cell dynamics involved in salivary gland homeostasis.
  • To explore the role of the extracellular matrix in salivary gland function and repair.

Main Methods:

  • Utilizing OMICS technologies (genomics, transcriptomics, proteomics, etc.) to analyze salivary gland tissues.
  • Investigating progenitor cell lineage dynamics during development and regeneration.
  • Analyzing the impact of the extracellular matrix microenvironment on salivary gland biology.

Main Results:

  • Detailed understanding of signaling pathways governing salivary gland development.
  • Characterization of progenitor cell behavior in homeostasis and regeneration.
  • Identification of the extracellular matrix's critical role in salivary gland function.

Conclusions:

  • Recent OMICS research provides a comprehensive framework for salivary gland regeneration.
  • This knowledge facilitates the development of advanced cell and gene therapies.
  • Bioengineering approaches can be guided by these findings to restore salivary function.