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Biological Compatibility Profile on Biomaterials for Bone Regeneration
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[Allergic reactions to bioimplants].

L Klimek1

  • 1Zentrum für Rhinologie und Allergologie, An den Quellen 10, 65183, Wiesbaden, Deutschland. Ludger.Klimek@Allergiezentrum.org.

HNO
|March 28, 2022
PubMed
Summary
This summary is machine-generated.

Otorhinolaryngologists should consider allergic reactions to bioimplants, such as cochlear implants (CI) and prostheses. This review analyzes the immunology of these reactions to improve patient care.

Keywords:
Bone cementsCochlear implantsDental implantsMethacrylatesOssicular prosthesis

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Area of Science:

  • Otorhinolaryngology
  • Immunology
  • Biomaterials Science

Background:

  • Bioimplants are widely utilized in otorhinolaryngology for procedures including facial reconstruction, cochlear implants (CI), bone-anchored hearing aids, and ossicular replacement prostheses (PORP/TORP).
  • Applications extend to tympanic drainage, laryngeal cannulas, voice prostheses post-laryngectomy, and dental implants.

Purpose of the Study:

  • To analyze the immunology of allergic reactions to bioimplants used in otorhinolaryngology.
  • To review the existing evidence on bioimplant allergies in this field.

Main Methods:

  • A comprehensive literature search was conducted.
  • Databases searched included Medline, PubMed, Cochrane Library, and national/international study and guideline registries.
  • Human studies published up to December 2021 were included.

Main Results:

  • A review of allergies to bioimplants in otolaryngology is presented, based on international literature and prior experience.
  • The review synthesizes current knowledge on the immunological aspects of bioimplant-related allergies.

Conclusions:

  • Otorhinolaryngologists must remain vigilant for potential allergic reactions when using allogeneic materials, especially bioimplants.
  • Awareness of allergy possibilities is crucial for safe and effective patient management.