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Related Concept Videos

Case Studies01:22

Case Studies

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There are many research methods available to psychologists in their efforts to understand, describe, and explain behavior and the cognitive and biological processes that underlie it.
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Methods of Documentation VI: Case Management Model01:15

Methods of Documentation VI: Case Management Model

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The case management model is a multidisciplinary approach that involves healthcare professionals from diverse disciplines, such as physicians, nurses, therapists, social workers, and pharmacists, working collaboratively to address the various needs of patients. Each healthcare professional brings unique expertise and perspectives, contributing to a more comprehensive understanding of the patient's condition and tailoring treatment plans accordingly.
For example, a patient with a chronic...
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Introduction to Documentation and Reporting01:20

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Documentation is the systematic process of formally recording, maintaining, and communicating information.
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Types of Reports II: Incident or Occurrence Report01:21

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An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
Purposes:
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SBAR II: Application of SBAR01:14

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SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
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Types of Reports III: Telephone and Verbal Reports01:26

Types of Reports III: Telephone and Verbal Reports

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Telephone and Verbal Reports in healthcare settings are two communication methods for conveying therapeutic instructions from healthcare providers to nurses or other healthcare staff.
Here's an overview of each type:
Telephone Orders
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Related Experiment Video

Updated: Sep 28, 2025

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

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Case Report.

B Almacan1, N Ozdemir2, H Gürkan3

  • 1"Celal Bayar" University, Faculty of Medicine, Department of Internal Medicine, Istanbul, Turkey.

Acta Endocrinologica (Bucharest, Romania : 2005)
|March 28, 2022
PubMed
Summary
This summary is machine-generated.

Thyroid hormone resistance (RTH) is a condition where the body doesn't respond properly to thyroid hormones. Genetic testing identified a specific THRβ gene mutation in a 22-year-old female patient presenting with RTH symptoms.

Keywords:
1034G>A (p.Gly345Asp)THRβThyroid Hormone Resistance

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Area of Science:

  • Endocrinology
  • Genetics
  • Molecular Biology

Background:

  • Thyroid hormone resistance (RTH) is characterized by diminished tissue response to thyroid hormones.
  • Nonspecific symptoms often complicate RTH diagnosis.
  • This case highlights a 22-year-old female with suspected RTH.

Observation:

  • The patient presented with fatigue, heat intolerance, and palpitations.
  • Physical examination revealed sweaty palms; laboratory results showed elevated TSH, fT3, and fT4.
  • Family history indicated hypothyroidism in her grandmother.

Findings:

  • Genetic analysis revealed a pathogenic variation NM_001128177.1 (THRβ): c.1034G > A (p.Gly345Asp) in the THRβ gene.
  • This specific mutation is associated with thyroid hormone resistance.

Implications:

  • Diagnosing RTH necessitates high clinical suspicion and genetic mutation analysis.
  • Genetic confirmation can prevent unnecessary and potentially harmful anti-thyroid treatments.
  • This case underscores the importance of genetic testing in RTH diagnosis.