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Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos
Published on: September 9, 2015
MYCOBACTERIUM ABSCESSUS SCLERAL BUCKLE INFECTION
Sophie Cai1,2, Ailin Song1, Durga S Borkar1
1Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina; and.
Purpose:
To report the successful management of a rare case of Mycobacterium abscessus scleral buckle infection.
Methods:
Case report.
Results:
A 63-year-old woman with a history of sarcoid anterior uveitis and macula-off retinal detachment repaired by scleral buckle and pars plana vitrectomy presented with eye pain, redness, and purulent drainage in the left eye. Slit-lamp examination showed superonasal scleral buckle exposure, purulent conjunctival discharge, corneal edema, nongranulomatous keratic precipitates, and anterior chamber cell and flare. The patient underwent urgent scleral buckle removal. Intraoperatively, an area of scleral thinning without perforation underneath the exposed buckle was discovered and covered with a scleral patch graft, and an amniotic membrane graft was used to cover an area of bare sclera with significant conjunctival scarring and retraction. Cultures grew M. abscessus panresistant except to amikacin. After 6 weeks of fortified amikacin drops and a long taper of topical steroid therapy for persistent postoperative anterior uveitis, the patient's symptoms resolved.
Conclusion:
Mycobacterium is an emerging causative agent of scleral buckle infections. Our report provides insights about the management of such cases.
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