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Related Experiment Video

Updated: Sep 28, 2025

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos

Published on: September 9, 2015

MYCOBACTERIUM ABSCESSUS SCLERAL BUCKLE INFECTION.

Sophie Cai^1,2, Ailin Song¹, Durga S Borkar¹

¹Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina; and.

Retinal Cases & Brief Reports

|March 28, 2022

Summary

A rare Mycobacterium abscessus infection of a scleral buckle was successfully managed. This case highlights the emerging role of Mycobacterium in buckle infections and effective treatment strategies.

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Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes

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Last Updated: Sep 28, 2025

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Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes

Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes

Published on: September 27, 2018

Area of Science:

Ophthalmology
Infectious Diseases
Microbiology

Background:

Scleral buckle surgery is a common procedure for retinal detachment repair.
Infections following scleral buckle placement can lead to significant morbidity.
Mycobacterium species are increasingly recognized as potential pathogens in ocular infections.

Observation:

A 63-year-old woman presented with symptoms of a scleral buckle infection, including eye pain, redness, and purulent discharge.
Examination revealed scleral buckle exposure, corneal edema, and anterior chamber inflammation.
Intraoperative findings included scleral thinning beneath the buckle, managed with a graft.

Findings:

Cultures identified Mycobacterium abscessus, panresistant to most antibiotics except amikacin.
The patient was treated with topical amikacin and a steroid taper for persistent uveitis.
Successful resolution of infection and inflammation was achieved with the prescribed treatment.

Implications:

Mycobacterium abscessus should be considered in the differential diagnosis of scleral buckle infections.
Prompt surgical intervention (buckle removal) and targeted antibiotic therapy are crucial for management.
This case underscores the importance of recognizing and treating rare microbial causes of post-surgical ocular infections.