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Review of Canadian trials of adjuvant endocrine therapy for breast cancer
NCI Monographs : a Publication of the National Cancer Institute
|January 1, 1986
Abstract:
Adjuvant ovarian ablation delays recurrence and prolongs survival in premenopausal patients with breast cancer, but the differences fall short of statistical significance; this effect is enhanced to statistically significant differences by low-dose prednisone. Adjuvant tamoxifen has delayed recurrence in post-menopausal patients with steroid receptor-positive tumors and positive axillary nodes, but, to date, has not affected survival.