Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inhaled Medications01:23

Inhaled Medications

429
Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
429
Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids01:25

Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids

422
Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
422
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

2.7K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.7K
Antiasthma Drugs: β2-Adrenoceptor Agonists01:25

Antiasthma Drugs: β2-Adrenoceptor Agonists

518
Bronchodilators are critical in managing asthma, a chronic respiratory condition characterized by airway constriction due to inflammation and hyper-reactivity. Specifically, bronchodilators ease this constriction by relaxing the bronchial muscles, facilitating easier breathing.
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce...
518
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

432
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
432
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

772
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
772

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Expression of the peanut diacylglycerol acyltransferase 3 increases the neutral lipid content and improves the fatty acid composition of <i>Chlorella vulgaris</i>.

Frontiers in plant science·2026
Same author

Protective Role for Itaconate During Inhaled Allergen Challenge.

Allergy·2025
Same author

System level changes are essential to improve the psychological wellbeing of NHS staff.

BMJ (Clinical research ed.)·2025
Same author

Community perinatal mental health teams reduced women's risk of mental illness relapse.

BMJ (Clinical research ed.)·2025
Same author

Incorporation of Patient and Public Involvement in Statistical Methodology Research: Summary of Workshop Proceedings.

Statistics in medicine·2025
Same author

What support do young carers find helpful?

BMJ (Clinical research ed.)·2025

Related Experiment Video

Updated: Sep 28, 2025

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.0K

Combination inhaler is effective in mild asthma.

Helen Saul1, Deniz Gursul1, Samantha Cassidy1

  • 1NIHR Centre for Engagement and Dissemination, Twickenham, UK.

BMJ (Clinical Research Ed.)
|March 29, 2022
PubMed
Summary

For adults and children with mild asthma, a combination inhaler with a fast-acting beta-agonist and steroid is effective when used as needed. This approach offers a convenient and efficient treatment option for managing mild asthma symptoms.

More Related Videos

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
07:28

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

Published on: April 6, 2017

40.9K
A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion
05:56

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion

Published on: May 12, 2023

4.0K

Related Experiment Videos

Last Updated: Sep 28, 2025

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.0K
Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
07:28

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

Published on: April 6, 2017

40.9K
A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion
05:56

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion

Published on: May 12, 2023

4.0K

Area of Science:

  • Respiratory Medicine
  • Pharmacology
  • Evidence-Based Medicine

Background:

  • Asthma is a chronic respiratory disease affecting millions worldwide.
  • Mild asthma is often managed with reliever inhalers, but the optimal strategy is debated.
  • Combination inhalers offer a potential for simplified and effective treatment.

Purpose of the Study:

  • To systematically review the evidence on the efficacy of fixed-dose combination inhalers (long-acting beta-agonist and inhaled corticosteroid) used as needed for mild asthma.
  • To compare this approach with traditional reliever-only inhaler strategies.

Main Methods:

  • A Cochrane systematic review was conducted.
  • Included studies assessed adults and children with mild asthma.
  • The review focused on outcomes such as symptom control, exacerbations, and lung function.

Main Results:

  • Combination inhalers used as needed demonstrated effectiveness in managing mild asthma.
  • This approach was found to be superior to using reliever-only inhalers in certain aspects of symptom control.
  • The review supports the use of these inhalers for prompt symptom relief and potentially better overall management.

Conclusions:

  • Fixed-dose combination inhalers used as needed are an effective treatment option for individuals with mild asthma.
  • This strategy offers a valuable alternative for managing mild asthma, potentially improving patient outcomes.
  • Further research may refine optimal usage patterns for different patient groups.