Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mutations01:35

Mutations

40.7K
Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
40.7K
Pigmentation01:19

Pigmentation

3.1K
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
3.1K
Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

6.0K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
6.0K
Skin Cancer01:30

Skin Cancer

4.8K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.8K
Lifestyle Factors and Health01:20

Lifestyle Factors and Health

142
Lifestyle factors play a critical role in maintaining overall health and preventing chronic diseases. Key elements, such as regular physical activity, a nutritious diet, and abstinence from smoking, can significantly enhance physical, mental, and emotional well-being while reducing the risk of several life-threatening conditions.
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
142
Benefits of Self-Esteem01:25

Benefits of Self-Esteem

5
Self-esteem—an individual's overall evaluation of their worth—plays a complex role in psychological functioning and well-being. It is often associated with many positive traits, such as confidence, optimism, and perseverance. Individuals with high self-esteem typically experience better sleep, manage peer pressure more effectively, and report greater life satisfaction. Conversely, low self-esteem has been consistently linked with increased risks of depression, anxiety, and poor...
5

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Risk factors associated with deep perineal wound dehiscence after second-degree perineal tears or episiotomy.

Acta obstetricia et gynecologica Scandinavica·2026
Same author

To distinguish solarium use with and without risk behavior on melanoma incidence and all-cause mortality: a report from the large MISS cohort.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology·2026
Same author

Intestinal neuroendocrine cells exposed to skim milk powder with a high content of Maillard reactants show an attenuated secretion of incretins.

Journal of dairy science·2026
Same author

ADNEX-AI: automated extraction of ultrasound predictors for interpretable ovarian cancer risk stratification.

NPJ precision oncology·2025
Same author

The importance of socioeconomic factors on antenatal identification of small for gestational age pregnancies: Exploring health inequalities in the antenatal care in Sweden.

Acta obstetricia et gynecologica Scandinavica·2025
Same author

Uric acid and future complications in young individuals with type 1 diabetes: results from the Diabetes Incidence Study in Sweden (DISS) and the National Diabetes Registry of Sweden (NDR).

Diabetologia·2025

Related Experiment Video

Updated: Sep 28, 2025

Studying Chronic Exposure of Mice to Ultraviolet B Radiation
03:20

Studying Chronic Exposure of Mice to Ultraviolet B Radiation

Published on: August 19, 2025

1.2K

Sun Exposure - Hazards and Benefits.

Pelle G Lindqvist1, Elisabeth Epstein2, Mona Landin-Olsson3

  • 1Department of Obstetrics and Gynecology, Södersjukhuset, and Department of Clinical Sciences and Education, Karolinska Institute, Stockholm, Sweden; Pelle.lindqvist@ki.se.

Anticancer Research
|March 29, 2022
PubMed
Summary

Sun exposure has carcinogenic effects, increasing skin cancer risk. However, moderate sun exposure may offer survival advantages and reduce risks for hypertension, diabetes, and cardiovascular disease.

Keywords:
UV exposurecancercardiovascular diseasediabetes mellitusmelanomamortalityreview

More Related Videos

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
12:37

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

18.4K
Assessment of Oxidative Damage in the Primary Mouse Ocular Surface Cells/Stem Cells in Response to Ultraviolet-C UV-C Damage
12:59

Assessment of Oxidative Damage in the Primary Mouse Ocular Surface Cells/Stem Cells in Response to Ultraviolet-C UV-C Damage

Published on: February 15, 2020

6.3K

Related Experiment Videos

Last Updated: Sep 28, 2025

Studying Chronic Exposure of Mice to Ultraviolet B Radiation
03:20

Studying Chronic Exposure of Mice to Ultraviolet B Radiation

Published on: August 19, 2025

1.2K
Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
12:37

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

18.4K
Assessment of Oxidative Damage in the Primary Mouse Ocular Surface Cells/Stem Cells in Response to Ultraviolet-C UV-C Damage
12:59

Assessment of Oxidative Damage in the Primary Mouse Ocular Surface Cells/Stem Cells in Response to Ultraviolet-C UV-C Damage

Published on: February 15, 2020

6.3K

Area of Science:

  • Dermatology
  • Public Health
  • Epidemiology

Background:

  • Sun exposure is linked to skin cancer, necessitating sun safety measures.
  • Fair-skinned individuals face higher skin cancer risks.
  • Recent evidence suggests potential benefits of sun exposure beyond risks.

Purpose of the Study:

  • To provide an updated, balanced, and evidence-based review of the hazards and benefits of sun exposure.
  • To re-evaluate sun safety guidelines in light of emerging data.

Main Methods:

  • This is a narrative review.
  • The review synthesizes existing literature on sun exposure, skin cancer, and other health outcomes.
  • Focus is on an evidence-based perspective.

Main Results:

  • While sun exposure increases skin cancer risk, fair-skinned women may have a survival advantage.
  • Inverse associations found between sun exposure and hypertension, thromboembolism, and type 2 diabetes mellitus.
  • Low sun exposure is linked to increased cardiovascular disease (CVD) and non-CVD/non-cancer mortality in women.
  • Vitamin D levels/sun exposure correlate with improved cancer prognosis.

Conclusions:

  • Sun safety guidelines require a more nuanced approach, balancing risks and benefits.
  • Moderate sun exposure may confer significant health benefits, including reduced risk of chronic diseases.
  • Further research is warranted to fully elucidate the complex relationship between sun exposure and overall health.