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Hypertensive Disorders of Pregnancy and Heart Failure Risk

Sarah A Goldstein1, Neha J Pagidipati2,3

  • 1Division of Cardiology, Duke University Medical Center, 2301 Erwin Rd, P.O. Box 3845, Durham, NC, 27710, USA. sarah.goldstein@duke.edu.

Current Hypertension Reports
|March 29, 2022
PubMed

Insights

Hypertensive disorders of pregnancy increase future heart failure risk. Early intervention and postpartum care are crucial for prevention, but optimal strategies remain unclear.

Area of Science:

  • Cardiology
  • Obstetrics
  • Public Health

Background:

  • Hypertensive disorders of pregnancy (HDP) are common and linked to long-term cardiovascular risks.
  • Heart failure (HF) is a significant future risk for women with a history of HDP.
  • HDP-related HF can manifest during pregnancy or years postpartum.

Purpose of the Study:

  • To review current data on the association between hypertensive disorders of pregnancy and heart failure risk.
  • To highlight the types of heart failure associated with HDP.
  • To underscore the need for improved prevention and management strategies.

Main Methods:

  • Literature review of studies on hypertensive disorders of pregnancy and heart failure.
  • Analysis of data linking HDP to various forms of heart failure.
  • Synthesis of findings regarding long-term cardiovascular outcomes post-HDP.

Main Results:

  • Hypertensive disorders of pregnancy are associated with increased risk of peripartum cardiomyopathy and HF with preserved ejection fraction.
  • Heart failure can develop during pregnancy or manifest years after delivery.
  • Mechanisms underlying HDP-associated HF require further elucidation.

Conclusions:

  • Hypertensive disorders of pregnancy represent a critical period for future heart failure risk.
  • Clear guidelines for risk stratification, postpartum care, and cardiovascular disease prevention in HDP patients are urgently needed.
  • Further research is essential to define optimal preventive measures against HDP-related heart failure.
Abstract

Keywords:
Heart failureHypertensive disorders of pregnancyPreeclampsia

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