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Updated: Sep 28, 2025

Author Spotlight: Integrating 2D-HPLC-MS and Molecular Networking in Natural Medicine Analysis
Published on: December 8, 2023
[Research progress on chemical constituents and pharmacological activities of Potentilla]
Jia Wu1, Zai-Qi Zhang2, Huang-He Yu1
1Traditional Chinese Medicine and Ethnomedicine Innovation & Development International Laboratory, Hunan University of Chinese Medicine Changsha 410208, China.
Abstract:
There are 200-500 species of Potentilla(Rosaceae) worldwide, among which 90 species are widely distributed in China and have a long history of ethnic medicinal use. According to our statistics, a total of 367 compounds have been isolated and identified from plants of this genus, including terpenoids, flavonoids, phenolic acids, tannins, and phenylpropanoids. The medicinal materials made from these plants mainly have antioxidative, blood sugar-lowering, anti-inflammatory, anti-tumor, cardiovascular system-protecting, neuroprotective, and hepatoprotective activities. This study systematically reviews the research progress on chemical constituents and pharmacological activities of Potentilla plants to provide a basis for further research and clinical application.
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