Related Experiment Video
Updated: Sep 28, 2025
08:42
Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
3.6K
When You Cannot Go With the Flow: A Case Report of May-Thurner Syndrome
Adnan Khan1, Jeffrey Wang1, Leslea Brickner1
1Department of Internal Medicine, Kaiser Permanente Oakland Medical Center, Oakland, CA.
The Permanente Journal
|March 29, 2022
Summary
May-Thurner syndrome (MTS) can cause left leg swelling and pain due to iliac vein compression. Further CT imaging is recommended if initial ultrasounds for deep vein thrombosis are negative.
Area of Science:
- Vascular Surgery
- Radiology
- Venous Thromboembolism
Background:
- May-Thurner syndrome (MTS) involves extrinsic compression of the left iliac vein, often leading to deep vein thrombosis (DVT).
- MTS predominantly affects women aged 20-50, presenting with unilateral leg swelling and pain.
Observation:
- A patient presented with back and left lower extremity pain and swelling.
- Initial duplex ultrasound was negative for deep venous thrombus.
Findings:
- Computed tomography (CT) revealed a venous thrombus in the left common, internal, and external iliac veins.
- Diagnosis of MTS was confirmed despite a negative initial ultrasound.
Implications:
- CT venography should be considered for unilateral lower extremity swelling when initial ultrasounds are negative for DVT.
- Early diagnosis and appropriate imaging are crucial for managing May-Thurner syndrome.
Related Concept Videos
01:29Cardiomyopathy III: Hypertrophic Cardiomyopathy
76
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
76
01:23Mitral Stenosis II: Clinical features and Diagnostic Tests
40
Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
40
01:22Mitral Stenosis I: Introduction
65
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
65
01:27Mitral Valve Prolapse I: Introduction
58
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
58
01:22Mitral Valve Prolapse II: Assessment and Management
50
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
50
01:26Mitral Stenosis III: Medical Management
32
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
32