Polycyclic aromatic hydrocarbons, long non-coding RNA expression, and DNA damage in coke oven workers

Jie Yu1, Miao Liu1, Qin Fang2

  • 1Department of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Rd., Wuhan, 430030, Hubei, China.

Summary

Long non-coding RNA NR_024564 may influence DNA damage in coke oven workers with over 20 years of exposure to polycyclic aromatic hydrocarbons (PAHs). Lower NR_024564 levels correlated with increased DNA damage markers, especially with higher PAH metabolite exposure.

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