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Updated: Sep 28, 2025

Detecting Wolbachia Strain wAlbB in Aedes albopictus Cell Lines
Published on: June 1, 2022
Cytoplasmic incompatibility: A Wolbachia toxin-antidote mechanism comes into view
1Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520, USA.
Abstract:
The Wolbachia cidA and cidB genes promote bacterial endosymbiont inheritance through the host female germline. CidB is now shown to load into maturing sperm nuclei. Following fertilization, it disrupts paternal chromosome condensation, triggering embryonic arrest if not countered by CidA in Wolbachia-infected eggs.
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