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Related Experiment Video

Updated: Sep 28, 2025

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
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ESHRE guideline: endometriosis.

Christian M Becker1, Attila Bokor2, Oskari Heikinheimo3

  • 1Nuffield Department of Women's and Reproductive Health, Endometriosis CaRe Centre, University of Oxford, Oxford, UK.

Human Reproduction Open
|March 30, 2022
PubMed
Summary
This summary is machine-generated.

This guideline offers 109 recommendations for diagnosing and managing endometriosis, covering pain, infertility, and various patient groups. It emphasizes best practices based on current evidence for improved patient care.

Keywords:
ESHRE guidelineadolescentendometriosisfertilityguidelinepelvic painsurgery

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Area of Science:

  • Gynecology
  • Reproductive Medicine
  • Clinical Guidelines

Background:

  • Endometriosis is a chronic condition with diverse presentations, primarily causing pain and infertility.
  • Current understanding highlights the complexity of endometriosis lesions and symptoms.

Purpose of the Study:

  • To provide evidence-based recommendations for the diagnosis and management of endometriosis.
  • To guide clinicians in delivering optimal care for women with endometriosis.

Main Methods:

  • Development of the guideline followed a structured methodology by the European Society of Human Reproduction and Embryology (ESHRE).
  • Literature searches up to December 2020 informed the formulation of key questions and recommendations.
  • Consensus was reached through specialist subgroups and the core guideline development group (GDG).

Main Results:

  • The guideline presents 109 recommendations on diagnosis, pain and infertility treatments, disease recurrence, and specific patient populations (adolescents, postmenopausal women).
  • It addresses diagnostic challenges, treatment options including medical and surgical interventions, and non-pharmacological approaches.
  • Five key areas required significant updates to previous recommendations, anticipating changes in clinical practice.

Conclusions:

  • The guideline offers clear advice on best practices for endometriosis care, supported by available scientific evidence.
  • Recommendations are provided for various clinical scenarios, though evidence for asymptomatic or extrapelvic endometriosis remains scarce.
  • A list of research recommendations is included to encourage further studies in endometriosis.