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[Gastroesophageal reflux and asthma].
Schweizerische Medizinische Wochenschrift
|September 27, 1986
Summary
Gastro-oesophageal reflux (GOR) is common in asthma and can worsen symptoms. Treating GOR with medication or surgery may improve asthma control in affected patients.
Area of Science:
- Pulmonology
- Gastroenterology
Context:
- Asthma is frequently associated with gastro-oesophageal reflux (GOR).
- GOR can trigger pulmonary symptoms through direct aspiration or reflex mechanisms.
- Oesophageal acidification exacerbates bronchial hyperreactivity in asthmatics.
Purpose:
- To investigate the link between GOR and asthma exacerbation.
- To highlight the potential for a vicious cycle between asthma medications and GOR.
- To recommend diagnostic and therapeutic strategies for GOR in asthma patients.
Summary:
- Asthma patients often experience GOR, which can lead to bronchospasm and increased bronchial hyperreactivity.
- Certain asthma medications can lower oesophageal sphincter pressure, worsening GOR.
- Anti-reflux therapies have shown efficacy in improving asthma symptoms in patients with confirmed GOR.
Impact:
- Highlights the importance of considering GOR in asthma management.
- Suggests 24-hour oesophageal pH monitoring for diagnosis.
- Recommends H2 receptor antagonists as a potential treatment for GOR-induced asthma symptoms.